Hepatitis

Overview

Hepatitis refers to an Inflammatory condition of the liver. It is commonly caused by a Viral Infection, but there are other possible causes of hepatitis. These include Autoimmune Hepatitis and hepatitis that occurs as a Secondary result of Medications, Drugs, Toxins, and Alcohol. Autoimmune hepatitis is a disease that occurs when your body makes antibodies against your liver tissue.

The liver is located in the Right upper area of your abdomen. It performs many critical functions that affect metabolism throughout the body, including:

  • Bile production, which is essential to digestion.
  • Filtering of toxins from your body.
  • Excretion of bilirubin (a product of broken-down red blood cells), Cholesterol, Hormones, and Drugs.
  • Breakdown of carbohydrates, fats, and proteins.
  • Activation of Enzymes, which are specialized proteins essential to body functions.
  • Storage of Glycogen (a form of sugar), Minerals, and Vitamins (A, D, E, and K).
  • Synthesis of blood proteins, such as albumin.
  • Synthesis of clotting factors.

According to the Centers for Disease Control and Prevention (CDC), approximately 4.4 million Americans are currently living with chronic hepatitis B and C. Many more people don’t even know that they have hepatitis.

Treatment options vary depending on which type of hepatitis you have. You can prevent some forms of hepatitis through immunizations and lifestyle precautions.

Types of Hepatitis

Viral infections of the liver that are classified as hepatitis include Hepatitis A, B, C, D, and E. A different virus is responsible for each type of virally transmitted hepatitis.

Hepatitis A is always an acute, short-term disease, while hepatitis B, C, and D are most likely to become ongoing and chronic. Hepatitis E is usually acute but can be particularly dangerous in pregnant women.

Hepatitis A

Hepatitis A is caused by an infection with the Hepatitis A Virus (HAV). This type of hepatitis is most commonly transmitted by consuming food or water contaminated by feces from a person infected with hepatitis A.

Hepatitis B

Hepatitis B is transmitted through Contact with Infectious Body Fluids, such as Blood, Vaginal Secretions, or Semen, Containing the Hepatitis B Virus (HBV). Injection drug use, having Sex with an Infected Partner, or Sharing Razors with an Infected Person increase your risk of getting hepatitis B. It’s estimated by the CDC that 1.2 million people in the United States and 350 million people worldwide live with this chronic disease.

Hepatitis C

Hepatitis C comes from the Hepatitis C virus (HCV). Hepatitis C is transmitted through Direct Contact with Infected Body Fluids, typically through Injection Drug Use and Sexual Contact. HCV is among the most common bloodborne viral infections in the United States. Approximately 2.7 to 3.9 million Americans are currently living with a chronic form of this infection.

Hepatitis D

Also called Delta Hepatitis, hepatitis D is a Serious Liver Disease caused by the Hepatitis D Virus (HDV). HDV is contracted through Direct Contact with Infected Blood. Hepatitis D is a Rare form of Hepatitis that only occurs in conjunction with hepatitis B infection. The hepatitis D virus can’t multiply without the presence of hepatitis B. It’s very uncommon in the United States.

Hepatitis E

Hepatitis E is a Waterborne Disease caused by the Hepatitis E Virus (HEV). Hepatitis E is mainly found in areas with poor sanitation and typically results from ingesting fecal matter that contaminates the water supply. This disease is uncommon in the United States. However, cases of hepatitis E have been reported in the Middle East, Asia, Central America, and Africa, according to the CDC.

Causes of Non Infectious Hepatitis

Alcohol and other Toxins

Excessive alcohol consumption can cause liver damage and inflammation. This is sometimes referred to as Alcoholic Hepatitis. The alcohol directly injures the cells of liver. Over time, it can cause permanent damage and lead to liver failure and cirrhosis, a thickening and scarring of the liver.

Other toxic causes of hepatitis include overuse or overdose of medications and exposure to poisons.

Autoimmune System Response

In some cases, the immune system mistakes the liver as a harmful object and begins to attack it. It causes ongoing inflammation that can range from mild to severe, often hindering liver function. It’s three times more common in women than in men.

Common Symptoms of Hepatitis

If one have infectious forms of hepatitis that are chronic, like hepatitis B and C, he/she may not have symptoms in the beginning. Symptoms may not occur until the damage affects liver function.

Signs and symptoms of acute hepatitis appear quickly. They include:

  • fatigue.
  • flu-like symptoms.
  • dark urine.
  • pale stool.
  • abdominal pain.
  • loss of appetite.
  • unexplained weight loss.
  • yellow skin and eyes, which may be signs of jaundice.

Chronic hepatitis develops slowly, so these signs and symptoms may be too subtle to notice.

Preventions

Hygiene

Practicing good hygiene is one key way to avoid contracting hepatitis A and E. If you’re traveling to a developing country, one should avoid:

  • Local water.
  • Ice.
  • Raw or undercooked shellfish and oysters.
  • Raw fruit and vegetables.

Hepatitis B, C, and D contracted through contaminated blood can be prevented by:

  • Not sharing drug needles.
  • Not sharing razors.
  • Not using someone else’s toothbrush.
  • Not touching spilled blood.

Hepatitis B and C can also be contracted through sexual intercourse and intimate sexual contact. Practicing safe sex by using condoms and dental dams can help decrease the risk of infection.

Vaccines

The use of vaccines is an important key to preventing hepatitis. Vaccinations are available to prevent the development of hepatitis A and B. Experts are currently developing vaccines against hepatitis C. A vaccination for hepatitis E exists in China, but it isn’t available in the United States.

Complications of Hepatitis

Chronic hepatitis B or C can often lead to more serious health problems. Because the virus affects the liver, people with chronic hepatitis B or C are at risk for:

  • Chronic liver disease.
  • Cirrhosis.
  • Liver cancer.

When liver stops functioning normally, liver failure can occur. Complications of liver failure include:

  • Bleeding disorders.
  • A buildup of fluid in your abdomen, known as Ascites.
  • Increased blood pressure in portal veins that enter your liver, known as Portal Hypertension.
  • Kidney Failure.
  • Hepatic Encephalopathy, which can involve Fatigue, Memory loss, and diminished mental abilities due to the buildup of toxins, like Ammonia, that affect brain function.
  • Hepatocellular Carcinoma, which is a form of liver cancer.
  • Death.

People with chronic hepatitis B and C are encouraged to Avoid Alcohol because it can Accelerate liver disease and failure. Certain supplements and medications can also affect liver function. If you have chronic hepatitis B or C, check with your doctor before taking any new medications.

Diagnosis

Following measures should be taken while making a diagnosis:

  • History.
  • General Physical Examination.
  • Liver Function Tests (LFT).
  • Blood tests.
  • Ultrasound.
  • Biopsy.

Treatment